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| Tumor Type | Myc Gene Type | Cause of Myc de-reg1 | No. of Cases | % with Myc Dereg. | Incr. Myc2 R P | Clin./Path correl. (+/-) | Molec. Correl. (+/-) | Reference(s) | Tumor Type | | Prost. |
c-myc |
Amp |
144 Stage III |
54 |
- |
+prog. dis, -survival |
Loss of Chr 8 cen |
10491435 |
Prost. |
| Prost. |
c-myc |
Amp |
61 |
29 |
- |
+Gleason, +prog. dis |
- |
11796839 |
Prost. |
| Prost. |
c-myc |
Amp |
223- P16, 32- BPH15, 62- M18, 54 –LR17 |
<2, 0, 11, 4 |
- |
- |
- |
10029066 |
Prost. |
| Prost. |
c-myc |
Overexp |
33 |
58 |
RNA |
- |
+hTert |
10754496 |
Prost. |
| Prost. |
c-myc |
Overexp |
48- PIN19, 71- P, 23- M |
0, 11, 91 |
Prot, Prot, Prot |
+grade |
- |
9012485 |
Prost. |
| Prost. |
c-myc |
Amp |
22 hormone refract. |
29>3-fold, 77 ->2-fold |
|
- |
- |
9665474 |
Prost. |
| Rhabdo. |
N-myc |
Amp |
6-embry., 7-alveolar |
0, 43 |
- |
- |
- |
8156531 |
Rhabdo. |
| Rhabdo. |
N-myc |
Amp |
14 –embry., 15-alveolar |
0, 60 |
- |
- |
- |
9872655 |
Rhabdo. |
| Rhabdo.. |
N-myc |
Amp |
7-embry., 6-alveolar |
0, 67 |
- |
- |
- |
2323837 |
Rhabdo.. |
| Small cell lung |
c-myc, L-myc, N-myc |
Amp |
183, , |
10, 2, 7 |
- |
- |
- |
1327035 |
Small cell lung |
| Sububgual |
c-myc |
Overexp |
24 |
100 |
Prot |
+relapse |
- |
9038509 |
Sububgual |
| Uveal melanoma |
c-myc |
Amp |
40 |
70 |
- |
+size |
3, Monosomy |
11431428 |
Uveal melanoma |
| Uveal Melanoma |
c-myc |
Overexp |
71 |
70 |
Prot |
+survival, esp. if Bcl-2 incr. |
+Bcl-2 |
10209447 |
Uveal Melanoma |
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There are 93 studies in this Myc database. Use the numbers below to page through the studies.
1 | 2 | 3 | 4 | 5 | |
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Last Updated: 04/14/03
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Funded by a grant from the National Library of Medicine
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